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Research

What is the Research Committee?

The CSVS research committee is compromised of the chair and five (5) members chosen by the chair and ratified by the Executive. The committee adjudicates various awards, holds research meetings as required and advises the Executive on matters pertaining to furthering Vascular Research in Canada. The committee has a mandate of 3 years.

What is the Research Interest Group?

The CSVS Research Interest Group is comprised of members with an interest in research. The group meets two to three times a year to discuss nation wide projects. This group is open to all CSVS members.

CSVS Publications

Screening for abdominal aortic aneurysms in Canada: 2020 review and position statement of the Canadian Society for Vascular Surgery

Varun Kapila, MD, Prasad Jetty, MD, MSc, Doug Wooster, MD, Vic Vucemilo, MD Luc Dubois, MD, MSc; on behalf of the Canadian Society for Vascular Surgery


 CSVS Current Research Projects

SHORT NECK/ JUXTA RENAL ANEURYSM TRIAL INFO COMING SOON

 CSVS Past Research Projects

A Canadian multicenter experience describing outcomes after endovascular abdominal aortic aneurysm repair stent graft explantation Luc Dubois 1 , John Harlock 2 , Heather L Gill 3 , Jerry C Chen 4 , Pascal Rheaume 5 , Prasad Jetty 6 , April J Boyd 7 , Graham Roche-Nagle 8 , Canadian Vascular Surgery Research Group Collaborators

Canadian Vascular Surgery Research Group: Andrew Hill, David Kopriva, Min Lee, Mark Nutley, Rob Gowing, Varun Kapila

Affiliations

1
. Division of Vascular Surgery, Department of Surgery, Western University, London, Ontario, Canada; Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada. Electronic address: Luc.Dubois@lhsc.on.ca.
2 . Division of Vascular Surgery, McMaster University, Hamilton, Ontario, Canada.
3 . McGill University, Montreal, Quebec, Canada.
4 . University of British Columbia, Vancouver, British Columbia, Canada.
5 . Laval University, Quebec City, Quebec, Canada.
6 . University of Ottawa, Ottawa, Ontario, Canada.
7 . University of Manitoba, Winnipeg, Manitoba, Canada.
8 . University of Toronto, Toronto, Ontario, Canada.

Awards

CSVS CLINICAL INVESTIGATOR AWARD


Dr. Graham Roche-Nagle, University of Toronto

MOBILE PHONE-BASED BLOOD PRESSURE AND SYMPTOM TELE MONITORING FOR TYPE B DISSECTION MANAGEMENT

CSVS YOUNG INVESTIGATOR AWARD


Dr. Charles de Mestral

UNDERSTANDING THE HEIGHTENED AMPUTATION RISK AMONG PEOPLE EXPERIENCING HOMELESSNESS: A POPULATION-BASED COHORT STUDY

CSVS RESIDENT RESEARCH AWARD



Dr. Xheni Konci, McGill University

Validation of the Comprehensive Complication Index in Vascular Surgery for Open Abdominal Aortic Aneurysm Repair



Dr. Ben Li, University of Toronto

Using machine learning to predict outcomes following open abdominal aortic aneurysm repair

CSVS NATIONAL STUDENT RESEARCH AWARD


Allen Li, The Ottawa Hospital

Reproducibility and Fragility of Published Randomized Controlled Trials Examining Surgical and Percutaneous Cardiovascular Interventions: A Meta-Epidemiological Study


Johann-Christoph Licht, University of Limerick, Ireland

Barriers to the prescription of ACE inhibitors in patients with Peripheral arterial disease or related cardiovascular disease


Lisa Vi, University of Toronto

Does Rural/urban and local/non-local status impact long-term outcomes for elective infrarenal endovascular aneurysm repair?


Nitish Bhatt, University of Toronto

Automated and Interpretable Multi-Modal Deep Learning Analysis for Carotid Plaque Analysis


 Bi-Annual Highlights of Canadian Publications

Aorta

Bradley NL, Leeper RJ, Roberts DJ, Ball C, Beckett A, Engels P, Joos E, Khwaja K, Kirkpatrick A, Lampron J, Minor S, Parry N, Rezende Neto JB, Widder S, Ahmed N, Gomez D, Kim MJ, Murphy PB, Rice T, Vogt K. Resuscitative endovascular balloon occlusion of the aorta (REBOA) in Canada: a context-specific consensus statement from the CANadian Collaborative on Urgent Care Surgery (CANUCS). Canadian Journal of Surgery. 2022 May 11;65(3):E310-E316 [journal impact factor: 2.544]. PMID: 35545282.
University of Ottawa

Ibrahim M, Lindsay TF, Chung JCY, Tan KT, Contreras J, Ouzounian M. Endovascular arch repair using the NEXUS arch endograft. Ann Cardiothorac Surg. 2022 Jan;11(1):62-64. doi: 10.21037/acs-2021-taes-18. PMID: 35211391; PMCID: PMC8807411.
University of Toronto

Boyd AJ. Intraluminal thrombus: Innocent bystander or factor in abdominal aortic aneurysm pathogenesis? JVS Vasc Sci. 2021 May 18;2:159-169. doi: 10.1016/j.jvssci.2021.02.001. PMID: 34617066; PMCID: PMC8489244.
University of Manitoba

Nishath T, Wright K, Burke CR, Teng X, Cotter N, Yi JA, Drudi LM; Aortic Dissection Collaborative. Implementation of telemedicine in the care of patients with aortic dissection. Semin Vasc Surg. 2022 Mar;35(1):43-50. doi: 10.1053/j.semvascsurg.2022.02.001. Epub 2022 Feb 17. PMID: 35501040.
l'Université de Montréal (CHUM)

Dion D, Drudi LM, Beaudoin N, Blair JF, Elkouri S. Safety of transition from a routine to a selective intensive care admission pathway after elective open aneurysm repair. Can J Surg. 2021 Jan 7;64(1):E3-E8. doi: 10.1503/cjs.012518. PMID: 33411997; PMCID: PMC7955835.
l'Université de Montréal (CHUM)

Li B, Rizkallah P, Eisenberg N, Forbes TL, Roche-Nagle G. Thresholds for abdominal aortic aneurysm repair in Canada and United States. J Vasc Surg. 2022 Mar;75(3):894-905. doi: 10.1016/j.jvs.2021.08.091. Epub 2021 Sep 29. PMID:34597785.
University of Toronto

Ramsay L, Richardson M, Sander B, Rahal M, Wu D, Setterfield M, Woodward G, Al-Omran M; COVID-19 Mod Collab group, de Mestral C. Predicting surgery waiting list volumes and health outcomes among people with an abdominal aortic aneurysm. Br J Surg. 2021 Jun 22;108(6):e221-e223. doi: 10.1093/bjs/znab074. PMID:33748853.
University of Toronto

Rocha RV, de Mestral C, Tam DY, Lee DS, Al-Omran M, Austin PC, Forbes TL, Ouzounian M, Lindsay TF. Health care costs of endovascular compared with open thoracoabdominal aortic aneurysm repair. J Vasc Surg. 2021 Jun;73(6):1934-1941.e1. doi: 10.1016/j.jvs.2020.09.034. Epub 2020 Oct 21. PMID: 33098943.
University of Toronto

Carotid

Jacob-Brassard J, Al-Omran M, Haas B, Nathens AB, Gomez D, Dueck AD, Forbes TL, de Mestral C. A multicenter retrospective cohort study of blunt traumatic injury to the common or internal carotid arteries. Injury. 2022 Jan;53(1):152-159. doi: 10.1016/j.injury.2021.07.035. Epub 2021 Jul 30. PMID: 34376278.
University of Toronto

Li B, Rizkallah P
, Eisenberg N, Forbes TL, Roche-Nagle G. Symptom Status of Patients Undergoing Carotid Endarterectomy in Canada and United States. Ann Vasc Surg. 2022 Apr;81:183-195. doi: 10.1016/j.avsg.2021.10.034. Epub 2021 Nov 12. PMID: 34780953.
University of Toronto

Fortin W, Chaput M, Elkouri S, Beaudoin N, Blair JF. Carotid endarterectomy after systemic thrombolysis in a stroke population. J Vasc Surg. 2020 Apr;71(4):1254-1259. doi: 10.1016/j.jvs.2019.05.061. Epub 2019 Sep 13. PMID: 31526691.
Hôpital du Sacré-Coeur de Montréal

Charbonneau P, Bonaventure PL, Drudi LM, Beaudoin N, Blair JF, Elkouri S. An institutional study of time delays for symptomatic carotid endarterectomy. J Vasc Surg. 2016 Dec;64(6):1726-1733. doi: 10.1016/j.jvs.2016.06.100. Epub 2016 Sep 20. PMID: 27663929.
l'Université de Montréal (CHUM)

Peripheral Arterial Disease

Abramson BL, Al-Omran M, Anand SS, Albalawi Z, Coutinho T, de Mestral C, Dubois L, Gill HL, Greco E, Guzman R, Herman C, Hussain MA, Huckell VF, Jetty P, Kaplovitch E, Karlstedt E, Kayssi A, Lindsay T, Mancini GBJ, McClure G, McMurtry MS, Mir H, Nagpal S, Nault P, Nguyen T, Petrasek P, Rannelli L, Roberts DJ, Roussin A, Saw J, Srivaratharajah K, Stone J, Szalay D, Wan D. Canadian Cardiovascular Society 2022 guidelines for peripheral arterial disease. Canadian Journal of Cardiology. 2022 May;38(5):560-587. [journal impact factor: 5.352]. PMID: 35537813.
Multiple Canadian Institutions

Alsuwailem B, Zamzam A, Syed MH, Greco E, Wheatcroft M, de Mestral C, Al-Omran M, Harlock J, Eikelboom J, Singh KK, Abdin R, Qadura M. Elevated plasma levels of NT-proBNP in ambulatory patients with peripheral arterial disease. PLoS One. 2021 Jul 21;16(7):e0253792. doi: 10.1371/journal.pone.0253792. PMID:34288948; PMCID: PMC8294530.
Multiple Canadian Institutions

Arfan S, Zamzam A, Syed MH, Jain S, Jahanpour N, Abdin R, Qadura M. The Clinical Utility of D-Dimer and Prothrombin Fragment (F1+2) for Peripheral Artery Disease: A Prospective Study. Biomedicines. 2022 Apr 11;10(4):878. doi: 10.3390/biomedicines10040878. PMID: 35453628; PMCID: PMC9028031.
University of Toronto

Bernatchez J, Mayo A, Kayssi A. The epidemiology of lower extremity amputations, strategies for amputation prevention, and the importance of patient-centered care. Semin Vasc Surg. 2021 Mar;34(1):54-58. doi: 10.1053/j.semvascsurg.2021.02.011. Epub 2021 Feb 7. PMID: 33757636.
University of Toronto

de Mestral C, Gomez D, Wilton AS, Lee DS, Albalawi Z, Austin PC, Jacob- Brassard J, Urbach DR, Al-Omran M, Baxter NN. A Population-Based Analysis of Diabetes-Related Care Measures, Foot Complications, and Amputation During the COVID-19 Pandemic in Ontario, Canada. JAMA Netw Open. 2022 Jan 4;5(1):e2142354. doi: 10.1001/jamanetworkopen.2021.42354. PMID: 34985514; PMCID: PMC8733837.
University of Toronto

Erman A, Ramsay LC, Sander B, Haj-Ali W, Wu D, Setterfield M, Rahal M, Woodward G, Al-Omran M, de Mestral C. Impact of COVID-19 on scheduled lower extremity revascularization for chronic limb-threatening ischemia. Br J Surg. 2021 Dec 17;109(1):e5-e7. doi: 10.1093/bjs/znab404. PMID: 34878108.
University of Toronto

Krantz MJ, Debus SE, Hsia J, Patel MR, Anand SS, Nehler MR, Hess CN, Capell WH, Bracken T, Szarek M, Mátyás L, Krievins DK, Nault P, Stefanov S, Haskell LP, Berkowitz SD, Muehlhofer E, Hiatt WR, Bauersachs RM, Bonaca MP. Low-dose rivaroxaban plus aspirin in older adults with peripheral artery disease undergoing acute limb revascularization. Insights from the VOYAGER PAD trial. Eur Heart J. 2021 Oct 14;42(39):4040-4048. doi: 10.1093/eurheartj/ehab408.PMID: 34430972 Clinical Trial.
Multiple Canadian Institutions

Debus ES, Nehler MR, Govsyeyev N, Bauersachs RM, Anand SS, Patel MR, Fanelli F, Capell WH, Brackin T, Hinterreiter F, Krievins D, Nault P, Piffaretti G, Svetlikov A, Jaeger N, Hess CN, Sillesen HH, Conte M, Mills J, Muehlhofer E, Haskell LP, Berkowitz SD, Hiatt WR, Bonaca MP. Effect of Rivaroxaban and Aspirin in Patients With Peripheral Artery Disease Undergoing Surgical Revascularization: Insights From the VOYAGER PAD Trial. Circulation. 2021 Oct 5;144(14):1104-1116. doi: 10.1161/CIRCULATIONAHA.121.054835. Epub 2021 Aug 12.PMID: 34380322 Clinical Trial.
Multiple Canadian Institutions

Georges G, Allard B, Dakkak M, Nourissat G, Febrer G. Appraising 5 years in activity of the largest public Canadian vascular graft bank. J Vasc Surg. 2021 Sep;74(3):972-978. doi: 10.1016/j.jvs.2021.02.022. Epub 2021 Mar 5. PMID: 33684476.
North Toronto Vascular

Roberts DJ, Nagpal S, Kubelik D, Brandys T, Stelfox HT, Lalu MM, Forster AJ, McCartney CJ, McIsaac DI. Association between neuraxial anaesthesia or general anaesthesia for lower limb revascularization surgery in adults and clinical outcomes: population-based comparative effectiveness study. The British Medical Journal (The BMJ). 2020 Nov 5;371:m4104 [journal impact factor: 30.223]. PMID: 33239330.
University of Ottawa

Roberts DJ, Murphy C, Strauss SA, Brandys T, Corrales-Medina V, Zhang J, Lalonde K, Meulenkamp B, Jennings A, Forster AJ, McIsaac DI, Nagpal SK. Structure, processes, and initial outcomes of The Ottawa Hospital Multi-Specialist Limb-Preservation Clinic and Programme: a unique-in-Canada quality improvement initiative. International Wound Journal. 2022 Feb;19(2):326-338 [journal impact factor: 2.825]. PMID: 34085390.
University of Ottawa

Roberts DJ, Nagpal SK, Forster AJ, Brandys T, Murphy C, Strauss SA, Vishnyakova E, Jennings A, Lawson J, McIsaac DI. Disability, pain, and wound-specific concerns self-reported by adults at risk of limb loss: a cross-sectional study using the World Health Organization Disability Assessment Schedule 2.0. Public Library of Science (PLoS) One. 2021 Jun 15;16(6):e0253288 [journal impact factor: 2.740]. PMID: 34129633.
University of Ottawa

Tong Y, Febrer G, Mao J, Wawryko P, Mao Y, Le-Bel G, How D, Philippe E, Zhou T, Zhang Z, Wang L, Germain L, Guidoin R. Limb salvage after aneurysmal degeneration of a cryopreserved vein allograft: Searching the autologous veins of the arm is worth the effort. Morphologie. 2020 Sep;104(346):202-213. doi: 10.1016/j.morpho.2020.05.001. Epub 2020 Jun 6. PMID: 32518049.

Wong KHF, Bosanquet DC, Ambler GK, Qureshi MI, Hinchliffe RJ, Twine CP; CLEAR survey collaborators. The CLEAR (Considering Leading Experts' Antithrombotic Regimes around peripheral angioplasty) survey: an international perspective on antiplatelet and anticoagulant practice for peripheral arterial endovascular intervention. CVIR Endovasc. 2019 Nov 12;2(1):37. doi: 10.1186/s42155-019-0079-8. Erratum in: CVIR Endovasc. 2020 Nov 27;3(1):87. PMID: 32026103; PMCID: PMC6966346.

Warren BE, Roche-Nagle G, Zhu J, Wang G, Eisenberg N, Rajan DK, Mafeld S. Endovascular community response to mortality data in use of paclitaxel devices for peripheral vascular disease. J Vasc Surg. 2021 Dec;74(6):2006-2013.e2. doi: 10.1016/j.jvs.2021.05.058. Epub 2021 Jun 26. PMID: 34182026.

Other (education, simulation, health services delivery, etc)

AlHamzah M, Hussain MA, Greco E, Zamzam A, Jacob-Brassard J, Wheatcroft M, Forbes TL, Al-Omran M. Trends in operative case volumes of Canadian vascular surgery trainees. J Vasc Surg. 2022 Feb;75(2):687-694.e3. doi:10.1016/j.jvs.2021.07.230. Epub 2021 Aug 28. PMID: 34461218.

Boyd AJ. Vascular Surgery in Canada: Challenges in the Great White North. Eur J Vasc Endovasc Surg. 2021 Dec;62(6):842-844. doi: 10.1016/j.ejvs.2021.08.025. Epub 2021 Oct 19. PMID: 34674933.

Drudi LM, Mitchell EL, Chandra V, Coleman DM, Hallbeck MS, Mannoia K, Money SR, Brown KR; SVS Wellness Task Force. A Gender-Based Analysis of Predictors and Sequelae of Burnout Amongst Practicing American Vascular Surgeons. J Vasc Surg. 2021 Oct 8:S0741-5214(21)02195-9. doi: 10.1016/j.jvs.2021.09.035. Epub ahead of print. PMID: 34634416.

Guidolin K, Catton J, Rubin B, Bell J, Marangos J, Munro-Heesters A, Stuart- McEwan T, Quereshy F. Ethical decision making during a healthcare crisis: a resource allocation framework and tool. J Med Ethics. 2021 May21:medethics-2021-107255. doi: 10.1136/medethics-2021-107255. Epub ahead of print. PMID: 34021059; PMCID: PMC8142675.

Javidan AP, Li A, Lee MH, Forbes TL, Naji F. A Systematic Review and Bibliometric Analysis of Applications of Artificial Intelligence and Machine Learning in Vascular Surgery. Ann Vasc Surg. 2022 Mar 24:S0890-5096(22)00148-0. doi: 10.1016/j.avsg.2022.03.019. Epub ahead of print. PMID: 35339595.

Lee MH, Li PY, Li B, Shakespeare A, Samarasinghe Y, Feridooni T, Cuen-Ojeda C, Alshabanah L, Kishibe T, Al-Omran M. A systematic review and meta-analysis of sex- and gender-based differences in presentation severity and outcomes in adults undergoing major vascular surgery. J Vasc Surg. 2022 Mar5:S0741-5214(22)00393-7. doi: 10.1016/j.jvs.2022.02.030. Epub ahead of print. PMID: 35257798.

Li B, Jacob-Brassard J, Dossa F, Salata K, Kishibe T, Greco E, Baxter NN, Al-Omran M. Gender differences in faculty rank among academic physicians: a systematic review and meta-analysis. BMJ Open. 2021 Nov 2;11(11):e050322. doi: 10.1136/bmjopen-2021-050322. PMID: 34728447; PMCID: PMC8565568.

Li B, Feridooni T, Cuen-Ojeda C, Kishibe T, de Mestral C, Mamdani M, Al- Omran M. Machine learning in vascular surgery: a systematic review and critical appraisal. NPJ Digit Med. 2022 Jan 19;5(1):7. doi: 10.1038/s41746-021-00552-y. PMID: 35046493; PMCID: PMC8770468.

Roy M, Todorov A, Ruel M, Elkouri S, Hardy JF. Anticoagulation Obtained below the Arterial Clamp Using a Single Fixed Bolus of Heparin in Vascular Surgery: A Pilot Study. Ann Vasc Surg. 2018 Jul;50:242-248. doi: 10.1016/j.avsg.2017.11.060. Epub 2018 Feb 23. PMID: 29481926.

Rubin B, Goldfarb R, Satele D, Graham L. Burnout and distress among allied health care professionals in a cardiovascular centre of a quaternary hospital network: a cross-sectional survey. CMAJ Open. 2021 Jan 11;9(1):E29-E37. doi: 10.9778/cmajo.20200059. PMID: 33436453; PMCID: PMC7843078.

Rubin B, Goldfarb R, Satele D, Graham L. Burnout and distress among nurses in a cardiovascular centre of a quaternary hospital network: a cross-sectional survey. CMAJ Open. 2021 Jan 11;9(1):E19-E28. doi: 10.9778/cmajo.20200058. PMID: 33436452; PMCID: PMC7843080.

Rubin B, Goldfarb R, Satele D, Graham L. Burnout and distress among physicians in a cardiovascular centre of a quaternary hospital network: a cross-sectional survey. CMAJ Open. 2021 Jan 11;9(1):E10-E18. doi:10.9778/cmajo.20200057. PMID: 33436451; PMCID: PMC7843077.

AV Access

Li B, Abdelmasih M, Eisenberg N, Lok C, Roche-Nagle G. Long-term outcomes following thrombolysis of arteriovenous grafts. J Vasc Access. 2021 Nov 19:11297298211027470. doi: 10.1177/11297298211027470. Epub ahead of print. PMID:34796766.
University of Toronto

Roberts DJ, Clarke A, Elliott M, King-Shier K, Hiremath S, Oliver M, Quinn RR, Ravani P. Association between attempted arteriovenous fistula creation and mortality in people starting hemodialysis via a catheter: a multicenter, retrospective cohort study. Canadian Journal of Kidney Health and Disease. 2021 Jul 30;8:20543581211032846 [journal impact factor: 1.780]. PMID: 34377500.
University of Ottawa

Basic Science

Botts SR, Fish JE, Howe KL. Dysfunctional Vascular Endothelium as a Driver of Atherosclerosis: Emerging Insights Into Pathogenesis and Treatment. Front Pharmacol. 2021 Dec 22;12:787541. doi: 10.3389/fphar.2021.787541. PMID: 35002720; PMCID: PMC8727904.

Gustafson D, Ngai M, Wu R, Hou H, Schoffel AC, Erice C, Mandla S, Billia F, Wilson MD, Radisic M, Fan E, Trahtemberg U, Baker A, McIntosh C, Fan CS, Dos Santos CC, Kain KC, Hanneman K, Thavendiranathan P, Fish JE, Howe KL. Cardiovascular signatures of COVID-19 predict mortality and identify barrier stabilizing therapies. EBioMedicine. 2022 Apr;78:103982. doi: 10.1016/j.ebiom.2022.103982. Epub 2022 Apr 8. PMID: 35405523; PMCID: PMC8989492.


 Contacts: Physician Leads For Research Projects

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For research inquiries, please contact Dr. Derek Roberts, CSVS Research Chair at csvs@vascular.ca

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